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Life Science X-ray Scattering (LiX) beamline, 16-ID

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The LiX beamline is part of the Biological, Environmental, & Planetary Science Division (BEPSD) and Center for BioMolecular Structure. It is jointly funded by NIH/NIGMS and DOE-BER, which allow us to develop instrumentation suitable for research primarily in structural biology, biophysics, biomaterials, and biofuel. The two major experiments supported at LiX include biomolecular solution scattering & microbeam scanning/mapping.

Beamline schedule

Configurations

Solution scattering Scanning mapping and tomography General-purpose

Planned upgrade and on-going development

updated Mar 2025

  • Scattering detector upgrade
  • Robot upgrade
  • Multi-modal data analysis in-line LC
  • Co-flow for in-line LC
  • Sample delivery using droplet injectors for specialized experiments

Proposal guide

LiX accepts several types of user proposals.

  • General User, Rapid Access, Block Allocation Groups, Joint Bio-SAXS/Bio-SANS, and Proprietary
    • Rapid access (RA): valid for 1 cycle; submit any time
    • General user (GU): valid for 1 year; multiple beamlines
    • Block allocation group (BAG): valid for 2 years; multiple beamlines
  • Deadlines: Jan 31 (cycle 2), May 31 (cycle 3), Sep 30 (cycle 1 the following year)
  • Remember to submit beam time requests when you have an active GU proposal and reach out to beamline staff for scheduling